Charles E. Gaber
Assistant Professor, Pharmacy Systems, Outcomes & Policy
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About Heading link
Overview:
Dr. Gaber is an Assistant Professor in the Department of Pharmacy Systems, Outcomes, and Policy (PSOP) and a member of the Center for Pharmacoepidemiology and Pharmacoeconomic Research (CPR). Dr. Gaber is a pharmacoepidemiologist whose applied research focuses on the use and effectiveness of cancer-directed therapies in older adults diagnosed with poor prognosis malignancies. Recent projects have focused on evaluating the comparative effectiveness of treatments for digestive diseases and esophageal cancer using secondary data from claims databases and registries. He seeks to generate robust evidence from observational data by harnessing modern causal inference study design and analysis strategies, such as the target-trial emulation approach. Methodologically, he has explored how to increase the utility of statistical estimators for recurrent events when working with non-experimental data. Future work will examine heterogenous treatment effects of cancer treatments using predictive modeling. He is an active member of the International Society for Pharmacoepidemiology (ISPE), Society of Epidemiologic Research (SER), and the American Society of Clinical Oncology (ASCO).
Research Interests:
• Pharmacoepidemiology
• Causal inference
• Comparative effectiveness research
• Geriatric oncology
• Health services research
Teaching and Supervision Heading link
Independent Study (PSOP 596), 1/8/2024 – 4/26/2024
Concentration Research (PSOP 485), 8/21/2023 – 12/1/2023
Independent Study (PSOP 596), 8/21/2023 – 12/1/2023
Independent Study (PSOP 596), 1/9/2023 – 4/28/2023
Independent Study (PSOP 596), 8/22/2022 – 12/2/2022
Selected Grants
Leveraging Data Science Methods to Deliver Individualized Treatment Effects in Advanced Prostate Cancer, NIH KL2 CATS Scholar Award., 6/1/2024 - Present, No Obligated Amount Set; No Anticipated Amount Set
Selected Publications
Xue, Angela Z, Anderson, Chelsea, Cotton, Cary C, Gaber, Charles E, Feltner, Cynthia, Dellon, Evan S. (2024). Prevalence and Costs of Esophageal Strictures in the United States. Clinical Gastroenterology and Hepatology. doi:10.1016/j.cgh.2024.03.026.
Abdelaziz, Abdullah I, Hanson, Kent A, Gaber, Charles E, Lee, Todd A. (2024). Optimizing large real‐world data analysis with parquet files in R: A step‐by‐step tutorial. Pharmacoepidemiology and Drug Safety, 33, (3), e5728. doi:10.1002/pds.5728.
Kirkegård, Jakob, Gaber, Charles, Heide-Jørgensen, Uffe, Fristrup, Claus Wilki, Lund, Jennifer L, Cronin-Fenton, Deirdre, Mortensen, Frank Viborg. (2024). Effect of surgery versus chemotherapy in pancreatic cancer patients: a target trial emulation. Journal of the National Cancer Institute, djae024. doi:10.1093/jnci/djae024.
Gaber, Charles E, Sarker, Jyotirmoy, Abdelaziz, Abdullah I, Okpara, Ebere, Lee, Todd A, Klempner, Samuel J, Nipp, Ryan D. (2024). Pathologic complete response in patients with esophageal cancer receiving neoadjuvant chemotherapy or chemoradiation: A systematic review and meta‐analysis. Cancer Medicine, 13, (4), e7076. doi:10.1002/cam4.7076.
★ Gaber, Charles E, Cotton, Cary C, Eluri, Swathi, Lund, Jennifer L, Farrell, Timothy M, Dellon, Evan S. (2022). Autoimmune and viral risk factors are associated with achalasia: A case‐control study. Neurogastroenterology & Motility, 34, (7), e14312. doi:10.1111/nmo.14312.
★ Gaber, Charles E, Eluri, Swathi, Cotton, Cary C, Strassle, Paula D, Farrell, Timothy M, Lund, Jennifer L, Dellon, Evan S. (2022). Epidemiologic and Economic Burden of Achalasia in the United States. Clinical Gastroenterology and Hepatology, 20, (2), 342-352.e5. doi:10.1016/j.cgh.2021.02.035.
★ Gaber, Charles E, Kinlaw, Alan C, Edwards, Jessie K, Lund, Jennifer L, Stürmer, Til, Peacock Hinton, Sharon, Pate, Virginia, Bartelt, Luther A, Sandler, Robert S, Peery, Anne F. (2021). Comparative Effectiveness and Harms of Antibiotics for Outpatient Diverticulitis : Two Nationwide Cohort Studies.. Annals of Internal Medicine, 174, (6), 737-746. doi:10.7326/m20-6315.
★ Perez, Arielle J, Strassle, Paula D, Sadava, Emmanuel E, Gaber, Charles, Schlottmann, Francisco. (2020). Nationwide Analysis of Inpatient Laparoscopic Versus Open Inguinal Hernia Repair. Journal of Laparoendoscopic & Advanced Surgical Techniques, 30, (3), 292-298. doi:10.1089/lap.2019.0656.
★ Schlottmann, Francisco, Gaber, Charles, Strassle, Paula D, Patti, Marco G, Charles, Anthony G. (2019). Cholecystectomy Vs. Cholecystostomy for the Management of Acute Cholecystitis in Elderly Patients. Journal of Gastrointestinal Surgery, 23, (3), 503-509. doi:10.1007/s11605-018-3863-1.
Education
Degrees:
PhD, University of North Carolina, United States, 2022
MPH, University of Michigan, United States, 2015
BSPH, Tulane University, United States, 2013